| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 1,027 | 9,523 | 10,621 | |
| 2020 | R | 1,249 | 9,438 | 10,819 | |
| 2016 | R | 1,117 | 8,470 | 9,737 | |
| 2012 | R | 1,706 | 7,393 | 9,318 | |
| 2008 | R | 2,084 | 7,663 | 9,951 | |
| 2004 | R | 2,802 | 6,833 | 9,714 | |
| 2000 | R | 2,994 | 5,424 | 8,564 | |
| 1996 | R | 2,987 | 3,490 | 7,237 | |
| 1992 | R | 3,635 | 4,142 | 8,713 | |
| 1988 | R | 3,143 | 4,535 | 7,693 | |
| 1984 | R | 2,674 | 4,587 | 7,285 | |
| 1980 | D | 4,852 | 2,906 | 7,853 | |
| 1976 | D | 4,480 | 2,153 | 6,705 | |
| 1972 | R | 509 | 4,419 | 4,954 | |
| 1968 | R | 417 | 569 | 6,190 | |
| 1964 | R | 1,127 | 2,140 | 3,267 | |
| 1960 | D | 1,752 | 366 | 2,771 | |
| 1956 | D | 2,310 | 298 | 2,665 | |
| 1952 | D | 2,236 | 556 | 2,792 | |
| 1948 | D | 634 | 50 | 1,735 | |
| 1944 | D | 1,350 | 183 | 1,533 | |
| 1940 | D | 1,627 | 119 | 1,758 | |
| 1936 | D | 1,465 | 47 | 1,512 | |
| 1932 | D | 1,851 | 40 | 1,895 | |
| 1928 | D | 854 | 331 | 1,185 | |
| 1924 | D | 888 | 62 | 950 | |
| 1920 | D | 1,023 | 198 | 1,224 | |
| 1916 | D | 1,407 | 184 | 1,592 | |
| 1912 | D | 914 | 24 | 1,023 | |
| 1908 | — | — | — | — | |
| 1904 | — | — | — | — | |
| 1900 | D | 821 | 110 | 946 | |
| 1896 | D | 1,089 | 32 | 1,137 | |
| 1892 | D | 794 | 16 | 1,124 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Itawamba County, tucked against Alabama in northeast Mississippi, recorded an R+80 presidential margin in 2024, placing it among the state's most one-sided jurisdictions. Its population of roughly 22,000 is predominantly rural and white, typical of the Appalachian-adjacent hill country.
The unraveling was not abrupt. The Democratic margin in Itawamba County peaked at ninety-six points in 1932; it narrowed steadily over the late twentieth century. The 1984 election delivered the county to the Republican party for the first time in many years, by a margin of twenty-six points. By 2024, the margin had widened further.
The economic and demographic context is severe. Itawamba County's median household income of $55,546 is among the lowest of any county in the United States; 16% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Lamar County and Scott County.