| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 4,154 | 13,314 | 17,626 | |
| 2020 | R | 4,577 | 13,407 | 18,230 | |
| 2016 | R | 4,359 | 11,445 | 16,852 | |
| 2012 | R | 7,450 | 8,993 | 17,050 | |
| 2008 | R | 7,625 | 9,197 | 17,375 | |
| 2004 | R | 7,768 | 9,962 | 17,840 | |
| 2000 | R | 6,643 | 8,181 | 15,430 | |
| 1996 | D | 6,731 | 5,970 | 15,108 | |
| 1992 | D | 6,428 | 5,749 | 16,348 | |
| 1988 | R | 5,926 | 8,507 | 14,563 | |
| 1984 | R | 4,967 | 10,252 | 15,344 | |
| 1980 | R | 5,121 | 8,180 | 14,084 | |
| 1976 | R | 7,573 | 7,746 | 15,524 | |
| 1972 | R | 4,757 | 9,648 | 14,619 | |
| 1968 | R | 5,815 | 7,336 | 14,837 | |
| 1964 | D | 9,503 | 6,429 | 15,932 | |
| 1960 | R | 6,532 | 10,396 | 16,928 | |
| 1956 | R | 5,149 | 10,224 | 15,373 | |
| 1952 | R | 6,631 | 9,749 | 16,380 | |
| 1948 | R | 6,639 | 7,651 | 14,380 | |
| 1944 | R | 6,512 | 8,878 | 15,390 | |
| 1940 | R | 8,710 | 10,125 | 18,835 | |
| 1936 | D | 11,404 | 8,532 | 20,070 | |
| 1932 | D | 9,026 | 8,750 | 18,106 | |
| 1928 | R | 3,709 | 11,174 | 15,080 | |
| 1924 | R | 3,604 | 8,997 | 15,106 | |
| 1920 | R | 6,888 | 8,764 | 16,122 | |
| 1916 | D | 4,312 | 4,228 | 9,446 | |
| 1912 | R | 2,726 | 3,426 | 9,092 | |
| 1908 | R | 3,449 | 5,210 | 9,663 | |
| 1904 | R | 2,448 | 5,427 | 8,630 | |
| 1900 | R | 3,120 | 5,014 | 8,435 | |
| 1896 | R | 3,258 | 4,337 | 7,775 | |
| 1892 | R | 2,510 | 3,439 | 6,425 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Guernsey County, anchored by Cambridge in the Appalachian foothills, has shifted decisively toward Republican presidential candidates over the past decade, recording a 52-point margin in 2024 that reflects broader trends across rural southeastern Ohio.
The Democratic margin in Guernsey County peaked at nineteen points in 1964. By 2000 the county had flipped, voting Republican for the first time in many years. The 2024 margin was fifty-two points, the most Republican-leaning result in the county's modern history.
The economic context is the key. Guernsey County's median household income of $58,478 sits well below state and national norms, and 15% of residents live below the federal poverty line. The shift here is part of a broader realignment of working-class places across the country. The county's voting pattern over the last decade is most similar to that of Carroll County and Tuscola County.