| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 100,074 | 158,541 | 263,316 | |
| 2020 | R | 103,030 | 150,021 | 258,155 | |
| 2016 | R | 74,483 | 127,832 | 215,165 | |
| 2012 | R | 68,070 | 121,685 | 193,189 | |
| 2008 | R | 70,886 | 116,363 | 190,657 | |
| 2004 | R | 55,347 | 111,481 | 168,833 | |
| 2000 | R | 43,810 | 92,714 | 140,293 | |
| 1996 | R | 41,605 | 71,210 | 120,420 | |
| 1992 | R | 34,651 | 65,066 | 113,907 | |
| 1988 | R | 27,188 | 67,371 | 95,126 | |
| 1984 | R | 24,137 | 66,766 | 91,369 | |
| 1980 | R | 32,135 | 46,168 | 80,415 | |
| 1976 | R | 35,943 | 39,099 | 75,981 | |
| 1972 | R | 10,143 | 46,360 | 58,229 | |
| 1968 | R | 12,928 | 31,652 | 59,821 | |
| 1964 | R | 17,275 | 29,358 | 46,633 | |
| 1960 | R | 13,976 | 22,657 | 36,633 | |
| 1956 | D | 11,819 | 10,752 | 27,193 | |
| 1952 | R | 14,863 | 17,743 | 32,606 | |
| 1948 | D | 2,745 | 789 | 9,474 | |
| 1944 | D | 7,107 | 711 | 8,094 | |
| 1940 | D | 8,118 | 514 | 8,632 | |
| 1936 | D | 8,310 | 0 | 8,402 | |
| 1932 | D | 7,930 | 0 | 8,058 | |
| 1928 | D | 4,116 | 546 | 4,664 | |
| 1924 | D | 3,728 | 59 | 3,829 | |
| 1920 | D | 4,409 | 144 | 4,553 | |
| 1916 | D | 3,384 | 81 | 3,501 | |
| 1912 | D | 3,140 | 0 | 3,195 | |
| 1908 | D | 2,774 | 176 | 2,985 | |
| 1904 | D | 2,489 | 66 | 2,555 | |
| 1900 | D | 1,777 | 47 | 1,824 | |
| 1896 | D | 2,718 | 288 | 3,041 | |
| 1892 | D | 3,026 | 600 | 3,686 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Greenville County anchors South Carolina's Upstate manufacturing and tech corridor, and despite absorbing tens of thousands of new residents over the past decade, its presidential margins have held steady in the low-to-mid twenties for Republicans.
The shift began with civil rights. 1960 marked the realignment in Greenville County, by a twenty-four points margin. The Republican margin reached its widest at sixty-two points in 1972. The 2024 margin was twenty-two points.
The political shift has tracked, in Greenville County, the political shift of the South more broadly. A 67% non-Hispanic-white share, a median household income of $76,932, and a 11% poverty rate describe the demographic context. The county's voting pattern over the last decade is most similar to that of Hanover County and Escambia County.
