| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 5,867 | 14,404 | 20,628 | |
| 2020 | R | 6,002 | 14,121 | 20,538 | |
| 2016 | R | 5,597 | 12,577 | 18,966 | |
| 2012 | R | 6,704 | 11,242 | 17,946 | |
| 2008 | R | 7,498 | 12,160 | 19,658 | |
| 2004 | R | 8,068 | 11,467 | 19,535 | |
| 2000 | R | 7,540 | 8,138 | 15,909 | |
| 1996 | D | 7,342 | 5,827 | 15,183 | |
| 1992 | D | 6,894 | 5,891 | 17,322 | |
| 1988 | D | 7,778 | 7,162 | 15,055 | |
| 1984 | R | 6,095 | 10,083 | 16,257 | |
| 1980 | R | 5,687 | 8,044 | 14,246 | |
| 1976 | D | 6,832 | 6,398 | 13,348 | |
| 1972 | R | 2,968 | 9,288 | 12,591 | |
| 1968 | R | 3,919 | 5,499 | 11,825 | |
| 1964 | D | 7,395 | 5,695 | 13,090 | |
| 1960 | R | 5,801 | 7,508 | 13,309 | |
| 1956 | R | 5,939 | 7,296 | 13,235 | |
| 1952 | R | 6,714 | 7,731 | 14,445 | |
| 1948 | D | 7,156 | 3,951 | 11,107 | |
| 1944 | D | 6,846 | 5,557 | 12,410 | |
| 1940 | D | 9,019 | 6,419 | 15,481 | |
| 1936 | D | 10,090 | 4,917 | 15,056 | |
| 1932 | D | 10,833 | 4,775 | 15,608 | |
| 1928 | R | 5,010 | 10,555 | 15,632 | |
| 1924 | D | 7,070 | 6,363 | 14,202 | |
| 1920 | R | 3,801 | 4,567 | 8,622 | |
| 1916 | D | 2,052 | 1,524 | 4,006 | |
| 1912 | D | 1,900 | 1,713 | 4,110 | |
| 1908 | D | 1,584 | 1,528 | 3,274 | |
| 1904 | — | — | — | — | |
| 1900 | — | — | — | — | |
| 1896 | — | — | — | — | |
| 1892 | — | — | — | — | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Despite hosting the federally recognized Osage Nation and its nearly 21,000 enrolled members, the county has voted Republican by margins exceeding 40 points in recent presidential cycles, reflecting rural Oklahoma's broader electoral pattern.
The Republican margin in Osage County reached its widest at fifty points in 1972. The margin in 2024 was forty-one points, in line with the county's deep historical pattern.
Osage County's loyalty is rooted in its place. Median household income of $62,847, a 63% non-Hispanic-white share, and a population of 45,997 together describe a community whose political habits are deeply settled. The county's voting pattern over the last decade is most similar to that of Craig County and Nowata County.
