| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 13,891 | 45,728 | 60,451 | |
| 2020 | R | 13,645 | 42,907 | 57,546 | |
| 2016 | R | 10,354 | 36,236 | 49,049 | |
| 2012 | R | 11,156 | 33,474 | 45,549 | |
| 2008 | R | 11,691 | 32,552 | 45,128 | |
| 2004 | R | 10,287 | 29,759 | 40,510 | |
| 2000 | R | 8,927 | 24,681 | 34,582 | |
| 1996 | R | 8,369 | 17,151 | 27,900 | |
| 1992 | R | 8,275 | 17,008 | 29,494 | |
| 1988 | R | 6,103 | 17,448 | 23,696 | |
| 1984 | R | 4,481 | 15,155 | 19,764 | |
| 1980 | R | 7,789 | 9,575 | 17,923 | |
| 1976 | D | 8,505 | 8,029 | 16,655 | |
| 1972 | R | 2,255 | 11,776 | 14,296 | |
| 1968 | R | 2,016 | 6,873 | 13,313 | |
| 1964 | R | 3,506 | 5,882 | 9,391 | |
| 1960 | R | 2,546 | 4,201 | 6,747 | |
| 1956 | D | 1,847 | 1,747 | 4,278 | |
| 1952 | R | 2,865 | 3,096 | 5,961 | |
| 1948 | D | 435 | 165 | 1,944 | |
| 1944 | D | 1,662 | 211 | 2,468 | |
| 1940 | D | 2,122 | 76 | 2,198 | |
| 1936 | D | 2,678 | 0 | 2,728 | |
| 1932 | D | 2,685 | 0 | 2,742 | |
| 1928 | D | 1,110 | 192 | 1,302 | |
| 1924 | D | 1,044 | 35 | 1,082 | |
| 1920 | D | 955 | 63 | 1,018 | |
| 1916 | D | 1,139 | 7 | 1,198 | |
| 1912 | D | 815 | 0 | 848 | |
| 1908 | D | 1,241 | 56 | 1,297 | |
| 1904 | D | 914 | 6 | 920 | |
| 1900 | D | 933 | 60 | 993 | |
| 1896 | D | 1,261 | 170 | 1,431 | |
| 1892 | D | 603 | 129 | 1,196 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Pickens County sits in the Blue Ridge foothills and has delivered Republican presidential margins above 50 points in recent cycles, driven by a mix of rural townships and the college town of Clemson, whose university presence tempers but doesn't reverse the county's conservative lean.
The shift began with civil rights. 1980 marked the realignment in Pickens County, by a ten points margin. The Republican margin reached its widest at sixty-seven points in 1972. The 2024 margin was fifty-three points.
The political shift has tracked, in Pickens County, the political shift of the South more broadly. A 84% non-Hispanic-white share, a median household income of $61,064, and a 17% poverty rate describe the demographic context. The county's voting pattern over the last decade is most similar to that of Baldwin County and Jones County.
