| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | D | 22,832 | 13,750 | 36,970 | |
| 2020 | D | 27,295 | 13,603 | 41,205 | |
| 2016 | D | 26,318 | 11,931 | 38,910 | |
| 2012 | D | 30,720 | 12,022 | 43,041 | |
| 2008 | D | 27,263 | 12,115 | 39,754 | |
| 2004 | D | 24,698 | 12,695 | 37,564 | |
| 2000 | D | 19,802 | 12,657 | 32,734 | |
| 1996 | D | 18,610 | 10,494 | 30,315 | |
| 1992 | D | 18,440 | 11,328 | 32,234 | |
| 1988 | D | 14,655 | 13,281 | 28,049 | |
| 1984 | D | 15,121 | 14,286 | 29,636 | |
| 1980 | D | 16,178 | 11,313 | 27,733 | |
| 1976 | D | 13,652 | 8,794 | 22,604 | |
| 1972 | R | 7,652 | 11,711 | 19,745 | |
| 1968 | D | 8,971 | 5,144 | 21,259 | |
| 1964 | R | 5,607 | 10,456 | 16,063 | |
| 1960 | R | 3,890 | 5,233 | 9,123 | |
| 1956 | D | 2,511 | 1,467 | 6,921 | |
| 1952 | R | 2,829 | 4,695 | 7,524 | |
| 1948 | D | 435 | 164 | 3,763 | |
| 1944 | D | 2,440 | 87 | 2,693 | |
| 1940 | D | 2,356 | 56 | 2,412 | |
| 1936 | D | 2,947 | 0 | 3,006 | |
| 1932 | D | 2,643 | 0 | 2,757 | |
| 1928 | D | 1,545 | 92 | 1,637 | |
| 1924 | D | 1,727 | 67 | 1,807 | |
| 1920 | D | 2,526 | 304 | 2,831 | |
| 1916 | D | 2,641 | 159 | 2,831 | |
| 1912 | D | 1,550 | 0 | 1,685 | |
| 1908 | D | 2,687 | 405 | 3,093 | |
| 1904 | D | 2,941 | 238 | 3,179 | |
| 1900 | D | 2,457 | 167 | 2,624 | |
| 1896 | D | 2,729 | 282 | 3,011 | |
| 1892 | D | 2,792 | 838 | 3,637 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Orangeburg's electorate is majority Black, anchoring consistent Democratic margins that have exceeded 20 points in recent presidential cycles. The county seat hosts South Carolina State University, adding a student population to its historically rural demographic base.
The unraveling was not abrupt. The Democratic margin in Orangeburg County peaked at ninety-eight points in 1936; it narrowed steadily over the late twentieth century. The 1976 election delivered the county to the Republican party for the first time in many years, by a margin of twenty-one points. By 2024, the margin had settled into deep Republican territory.
The economic and demographic context is severe. Orangeburg County's median household income of $45,675 is among the lowest of any county in the United States; 22% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Williamsburg County and Lee County.
