| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 352 | 2,144 | 2,514 | |
| 2020 | R | 397 | 2,170 | 2,580 | |
| 2016 | R | 354 | 1,780 | 2,196 | |
| 2012 | R | 538 | 1,756 | 2,316 | |
| 2008 | R | 586 | 1,815 | 2,431 | |
| 2004 | R | 639 | 1,912 | 2,558 | |
| 2000 | R | 837 | 1,708 | 2,574 | |
| 1996 | D | 1,213 | 949 | 2,405 | |
| 1992 | D | 1,353 | 1,128 | 3,093 | |
| 1988 | D | 1,773 | 1,596 | 3,376 | |
| 1984 | R | 1,332 | 2,007 | 3,357 | |
| 1980 | R | 1,446 | 1,455 | 2,926 | |
| 1976 | D | 1,730 | 1,058 | 2,804 | |
| 1972 | R | 699 | 1,790 | 2,492 | |
| 1968 | D | 1,589 | 893 | 2,981 | |
| 1964 | D | 2,420 | 737 | 3,159 | |
| 1960 | D | 2,131 | 1,208 | 3,350 | |
| 1956 | D | 1,891 | 1,091 | 2,982 | |
| 1952 | D | 2,031 | 1,417 | 3,460 | |
| 1948 | D | 2,181 | 230 | 2,484 | |
| 1944 | D | 2,215 | 218 | 2,573 | |
| 1940 | D | 2,401 | 251 | 2,657 | |
| 1936 | D | 2,035 | 192 | 2,231 | |
| 1932 | D | 1,490 | 148 | 1,640 | |
| 1928 | R | 746 | 1,099 | 1,845 | |
| 1924 | D | 1,242 | 169 | 1,446 | |
| 1920 | D | 694 | 89 | 850 | |
| 1916 | D | 803 | 39 | 923 | |
| 1912 | D | 573 | 19 | 708 | |
| 1908 | — | — | — | — | |
| 1904 | — | — | — | — | |
| 1900 | — | — | — | — | |
| 1896 | — | — | — | — | |
| 1892 | — | — | — | — | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Mitchell County, anchored by the small city of Colorado City, delivered a 71-point Republican presidential margin in 2024 — a spread typical of sparsely populated West Texas oil-patch counties where GOP alignment has deepened steadily over two decades.
The unraveling was not abrupt. The Democratic margin in Mitchell County peaked at eighty-three points in 1916; it narrowed steadily over the late twentieth century. The 2000 election delivered the county to the Republican party for the first time in many years, by a margin of thirty-four points. By 2024, the margin had widened further.
The economic and demographic context is severe. Mitchell County's median household income of $60,550 is among the lowest of any county in the United States; 14% of residents live below the federal poverty line. The county's voting pattern over the last decade is most similar to that of Nolan County and Navarro County.