| Year | Won | Margin | Democratic | Republican | Total |
|---|---|---|---|---|---|
| 2024 | R | 2,463 | 5,651 | 8,227 | |
| 2020 | R | 2,490 | 5,649 | 8,355 | |
| 2016 | R | 2,025 | 4,860 | 7,457 | |
| 2012 | R | 2,561 | 4,258 | 6,982 | |
| 2008 | R | 2,915 | 4,033 | 7,092 | |
| 2004 | R | 2,275 | 5,018 | 7,386 | |
| 2000 | R | 2,208 | 4,178 | 6,662 | |
| 1996 | R | 2,279 | 3,290 | 6,505 | |
| 1992 | R | 2,038 | 2,960 | 6,838 | |
| 1988 | R | 2,616 | 3,724 | 6,366 | |
| 1984 | R | 1,869 | 4,679 | 6,596 | |
| 1980 | R | 1,471 | 4,611 | 6,559 | |
| 1976 | R | 2,436 | 3,715 | 6,237 | |
| 1972 | R | 1,718 | 4,815 | 6,533 | |
| 1968 | R | 1,508 | 3,840 | 5,822 | |
| 1964 | R | 3,169 | 3,626 | 6,795 | |
| 1960 | R | 2,543 | 5,057 | 7,600 | |
| 1956 | R | 2,296 | 5,275 | 7,571 | |
| 1952 | R | 1,939 | 6,082 | 8,021 | |
| 1948 | R | 2,515 | 4,060 | 6,575 | |
| 1944 | R | 2,664 | 5,291 | 7,955 | |
| 1940 | R | 2,927 | 5,799 | 8,726 | |
| 1936 | R | 4,173 | 4,399 | 8,634 | |
| 1932 | D | 4,752 | 3,119 | 7,959 | |
| 1928 | R | 2,959 | 5,063 | 8,077 | |
| 1924 | R | 2,208 | 3,245 | 6,475 | |
| 1920 | R | 1,671 | 3,869 | 5,722 | |
| 1916 | D | 2,344 | 2,121 | 4,566 | |
| 1912 | D | 1,945 | 922 | 4,040 | |
| 1908 | D | 2,411 | 2,243 | 4,743 | |
| 1904 | R | 1,420 | 2,616 | 4,445 | |
| 1900 | R | 2,327 | 2,718 | 5,154 | |
| 1896 | R | 2,384 | 2,438 | 4,988 | |
| 1892 | D | 1,591 | 937 | 4,243 | |
| 1888 | — | — | — | — | |
| 1884 | — | — | — | — | |
| 1880 | — | — | — | — | |
| 1876 | — | — | — | — |
Otoe County sits along Nebraska's eastern border with a small-city core in Nebraska City, yet its presidential margins have grown consistently rightward since 2004, reflecting rural consolidation patterns common across the Missouri River tier.
The Republican margin in Otoe County reached its widest at fifty-two points in 1952. The margin in 2024 was thirty-nine points, in line with the county's deep historical pattern.
Otoe County's loyalty is rooted in its place. Median household income of $82,188, a 87% non-Hispanic-white share, and a population of 16,241 together describe a community whose political habits are deeply settled. The county's voting pattern over the last decade is most similar to that of Dodge County and Nemaha County.
